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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetic Acid
drug:
Gabapentin
Research Papers that Mention the Interaction
“ Gabapentin (50 and 100 mg/kg), and dexamethasone considerably reduced macroscopic and microscopic colonic lesions induced by acetic acid in rats in comparison with colitis control group.”
An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats.“Conclusions These data demonstrate that gabapentin effectively inhibits acetic acid –induced nociception, and the antinociceptive effect of gabapentin correlates with the suppression of noxious-evoked release of excitatory amino acids in the spinal cord.”
“When compared to saline-treated rats, animals pretreated with 100 mg/kg gabapentin showed suppression of the acetic acid –induced increases in glutamate, aspartate, and serine concentrations.”
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