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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Acetic Acid and Duloxetine

supplement:

Acetic Acid

Research Papers that Mention the Interaction

…,duloxetine significantly increases bladder capacity … muscle activity in the catacetic acid bladder model by a central nervous system action that appears to be mediated via both motor and sensory afferent …,3]; and it has been suggested that duloxetine promotes urine storage by relaxing the bladder and increasing urethral resistance.
European urology  •  2006  |  View Paper
However, this duloxetine "pretreatment" did prevent the typical acetic acid-induced reductions in bladder capacity and unmasked a marked activation of sphincter EMG activity on acetic acid infusion (by 8-fold).
The Journal of pharmacology and experimental therapeutics  •  1995  |  View Paper