“On the other hand, 8-OH-DPAT, a full selective …-HT1A receptor agonist, prazosin, an alpha1-adrenoceptor antagonist, clonidine , an alpha2-adrenoceptor agonist, and two beta-adrenoceptor antagonists: propranolol and metoprolol, dose-… reduced the number of body writhes induced by intraperitoneally administered 2% solution of acetic acid (the … test).”