“On the other hand, 8-OH-DPAT, a full selective 5-HT1A receptor …, prazosin, an alpha1-adrenoceptor antagonist, clonidine, an alpha2-adrenoceptor agonist, and two beta-adrenoceptor antagonists : propranolol and metoprolol, dose-dependently reduced the number of … writhes induced by intraperitoneally administered 2% solution of acetic acid (the … test).”