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Last Updated: 2 months ago

Possible Interaction: Acetazolamide and Secretin

supplement:

Secretin

Research Papers that Mention the Interaction

The effect of secretin was partially inhibited by prior infusions of the carbonic anhydrase inhibitor, acetazolamide.
Gastroenterology  •  1969  |  View Paper
Summary Intravenous injection of 2-acetylamino −1,3,4 - thiadiazole-5-sulfonamide (compound No. 6063) in pancreatic fistula dogs results in a marked reduction in the volume output and the bicarbonate concentration of pancreatic secretion following stimulation with secretin.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1952  |  View Paper
Acetazolamide reduced bile HCO3- secretion in six secretin infused, bile-acid depleted pigs by 67 (58-71)% at arterial pH 7.41 (7.38-7.46).
Acta physiologica Scandinavica  •  1988  |  View Paper
In unanesthetized dogs with chronic gastric and pancreatic fistulas, an intravenous infusion of acetazolamide (Diamox), superimposed on a steady-state infusion of secretin , caused a prompt reduction in the volume and bicarbonate concentration of pancreatic secretion and a delayed reduction in potassium concentration.
Archives of surgery  •  1971  |  View Paper
Acetazolamide slightly augmented the bile flow but reduced the fiow response of the pancreas to secretin.
The American journal of physiology  •  1966  |  View Paper