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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Acetazolamide
supplement:
Potassium
Research Papers that Mention the Interaction
“ Potassium supplementation and acetazolamide provided remarkable improvement in the severity and frequency of her periodic weakness.”
A Girl with Palpitations and Periodic Weakness“A paradoxical, critical increase in potassium can result from a single 1000-mg iv dose of acetazolamide.”
“ ACZ is thought to potentiate potassium uptake into muscles.”
“The data suggest that acetazolamide administration alters potassium exchange rates between intracellular and extracellular compartments in such a way as to protect from sudden upward surges in plasma potassium levels.”
“The results with acetazoleamide suggest that it interferes with the distal tubular secretion of potassium.”
“However, net secretion of rubidium, as well as of potassium , could be demonstrated during periods of reduced filtration rate following administration of acetazoleamide.”
“ Acetazolamide administration suppressed the sodium and potassium absorption up to 90 and 100%, resp.,”
[Effect of acetazolamide on sodium and potassium absorption in the sheep forestomach].“Increasing doses of acetazolamide increased both sodium and potassium excretion in 5-day-old piglets.”
“Current studies in this laboratory indicate that humans treated with acetazolamide (250 mg q. 6 hr) have a lowered potassium entry rate from plasma into red blood cells and other large tissue pools of K+ probably muscle.”
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