Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“A decreased sensitivity of urea synthesis from glutamine to acetazolamide inhibition was also observed when the extracellular HCO3- and CO2 concentrations were varied from 0-50mM and 0-2.4mM, respectively.”
Biological chemistry Hoppe-Seyler • 1986 | View Paper
“In the functioning kidney, perfused with 10(-3)M L- or D-glutamine, AZ (10(-3)M) markedly reduced NH3 formation and increased glutamine excretion, results consistent with AZ inhibition of the in situ gamma-GT.”