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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetazolamide
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“Supratherapeutic doses of AZM , CBZ, PHT, TPM, and ZNS decreased extracellular levels of GABA , NE, DA, and 5-HT, without affecting Glu levels.”
“Therapeutically relevant doses of AZM , CBZ, TPM, and ZNS increased hippocampal extracellular levels of GABA , NE, DA, and 5-HT, while PHT had no effect.”
Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin“Drugs such as acetazolamide or amiloride can block GABA depolarization.”
“ Acetazolamide (0.1 mmol l-1) decreased the rate of fall of pHi caused by a step increase in CO2 partial pressure as well as by GABA , which indicates that the neurone contains carbonic anhydrase.”
“Application of acetazolamide (10(‐4) M) for 5 min or more produced a decrease of up to 60% in the maximum rate of fall of pHi at GABA concentrations higher than 20 microM. 8.”
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