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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetazolamide
supplement:
Caffeine
Research Papers that Mention the Interaction
“For a variety of pharmaceutical agents acetazolamide , mitomycin C, hydroxyurea, 5-fluorouracil), caffeine was shown to enhance the teratogenic effect of the agent.”
Coteratogenic effects of caffeine.“The increase in fetal malformations seen, especially right forelimb electrodactyly, was augmented at both dose levels of acetazolamide by concomitant exposure to caffeine.”
“This study provides evidence that a subteratogenic dose of caffeine can potentiate the teratogenic effect of acetazolamide in C57BL/6J mice when dams are treated on day 9 of gestation.”
“This study provides evidence that ACZM , coupled with a subteratogenic dose of caffeine can produce abnormalities in the "resistant" SWV mice, using the endpoint of exencephaly on day 8 of gestation.”
Acetazolamide with caffeine causes exencephaly in "resistant" SWV mice.
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