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Last Updated: 2 years ago

Possible Interaction: Acetanilides and Glutathione

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drug:

Acetanilides

supplement:

Glutathione

Research Papers that Mention the Interaction

“Different interactions with xenobiotic-metabolizing phase I and II enzymes were observed, and GSH showed a protective effect against the acetanilides in both cell lines.”

Glutathione-dependent cytotoxicity of the chloroacetanilide herbicides alachlor, metolachlor, and propachlor in rat and human hepatoma-derived cultured cells

Cell Biology and Toxicology • 2004 | View Paper

“Interestingly, the sensitivity of LC-IT-MS made it possible, for the first time, to detect chloroacetanilides that are conjugated with two GSH molecules, in addition to the known single GSH conjugates.”

Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry.

The Analyst • 2007 | View Paper

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