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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Vitamin A
Research Papers that Mention the Interaction
“In combination, retinol + acetaminophen caused a significantly greater depletion of GSH compared to corn oil + acetaminophen (0.36 +/- 0.11 vs 0.89 +/- 0.19 micromol/g, respectively, p < 0.05).”
Retinol potentiates acetaminophen-induced hepatotoxicity in the mouse: mechanistic studies.“After 7 days of retinol pretreatment, the hepatotoxicities of allyl alcohol, acetaminophen , and galactosamine were potentiated.”
“At the same time, deficiency of vitamin A amplified the paracetamol and voltaren toxicity and its excess exhibited protective effects.”
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