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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Methionine
Research Papers that Mention the Interaction
“Methionine has been shown to be effective in the treatment of acetaminophen toxicity and a combination preparation of acetaminophen and methionine may prevent toxicity.”
Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation.“The results reveal that, methionine significantly prevented the rise in transaminases levels produced by hepatotoxic doses of paracetamol and chloroquine.”
Paracetamol and conventional antimalarial drugs induced hepatotoxicity and its protection by methionine in rats.“ Acute paracetamol toxicity was also prevented by D- as well as by L-methionine.”
“Ingestion of ACAP for a prolonged period of time increased the methionine requirement for growth, maintenance of hepatic GSH level and protein synthesis, but did not affect the methionine requirement for methylation reactions.”
“The dose-dependent depletion of GSH, the trend toward an increase in ACAP-GSH-derived conjugate … GSH depletion by providing dietary methionine in excess of requirement indicate that prolonged ingestion of ACAP may increase the requirement for … and limit the availability of methionine and cysteine for …, and drug detoxification.”
“ L-Methionine , fed in place of sodium sulfate, unblocked leukemogenicity inhibition by p-hydroxyacetanilide.”
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