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Last Updated: 2 years ago

Possible Interaction: Acetaminophen and Kava

supplement:

Kava

Research Papers that Mention the Interaction

In rat primary hepatocytes, co-treatment with kava and APAP caused 100% loss of cell viability, while the treatment of kava or APAP alone caused ∼50% and ∼30% loss of cell viability, respectively.
Phytomedicine : international journal of phytotherapy and phytopharmacology  •  2011  |  View Paper
Further, the incidences of hepatotoxicity and nephrotoxicity may be augmented by acetaminophen when concomitantly used with the potentially hepatotoxic herbs Echinacea and kava , and with herbs containing salicylate (willow, meadowsweet), respectively.
Journal of clinical pharmacy and therapeutics  •  2002  |  View Paper