Possible Interaction: Acetaminophen and Glucose

“For this reason, glucose meters are checked for interference from commonly encountered substances, including acetaminophen.”

“ Acetaminophen (paracetamol) interferes with continuous glucose monitor (CGM) sensing, resulting in falsely elevated CGM glucose values in both sensors currently approved by the U.S. Food and Drug Administration (FDA).”

“ APAP markedly increased serum levels of creatinine, BUN, and glucose and decreased levels of albumin and total protein.”

“The administration of CCl4 and AAP caused significant (p<0.05) elevation in liver enzymes; alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and other biochemical parameters, bilirubin, glucose , triglyceride and kidney function markers: urea and creatinine.”

“We show that oral administration of D-glucose , but not of either D-fructose or sucrose, prevents LPS-induced liver injury, as well as liver injury and death induced by an overdose of acetaminophen.”

“Unexpectedly, the intestinal absorption of AA was increased and sulfation of AA decreased by co-administration of glucose.”

“ Abstract Paracetamol , at concentrations up to 10 mM, caused a reversible, concentration-dependent inhibition of respiration in isolated rat-kidney tubules metabolizing glucose , glutamine, lactate or glutamate.”

“Pre treatment with FEO (250 and 500 mg/kg body weight) for … count), biochemical parameters (AST, ALT, ALK, total bilirubin, total protein, glucose , albumin/globulin ratio, cholesterol and triglyceride), and the level of phase I and … P450, cytochromeb5, glutathione-S-transferase) which were obstructed by the administration of acetaminophen.”

“ Loss of paracetamol was reduced by maintaining a low process temperature and by the addition of dextrose as a solubility suppressant.”