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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Ferrous Sulfate
Research Papers that Mention the Interaction
“Concomitant … ferrous sulphate … paracetamol , decreased AUC8 from 42.88 +/- 3.8-34.25 +/- 2.8 microg h mL(-1) (p = 0.04) and Cmax from 18.75 +/- ….9 to 15.9 +/- 1.7 microg mL(-1) (p = 0.11), while no change in tmax (p = 0.5) was originated.”
Effects of iron on the pharmacokinetics of paracetamol in saliva.“Levels of alanine aminotransferase in serum of acetaminophen plus ferrous sulfate-treated mice were higher at 4 and 6 h than those of acetaminophen-treated mice, but not significantly different.”
Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress.
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