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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetaminophen and Calcium Supplement

Research Papers that Mention the Interaction

In contrast, 0.2% CA supplementation in the diet resulted in a moderate delay in progression of liver injury and significantly higher liver regeneration after APAP treatment.
The American journal of pathology  •  2013  |  View Paper
Several hepatotoxic agents with varied chemical mechanisms of toxicity acetaminophen , diquat, and CCl4) depress membrane calcium pumps and/or enhance the permeability of membranes to calcium.
Biochemical pharmacology  •  1989  |  View Paper
Acetaminophen also induced alterations in mitochondrial calcium levels and decreased the ability of isolated mitochondria to sequester calcium.
The Journal of biological chemistry  •  1989  |  View Paper
Acetaminophen produced a dose-related accumulation of calcium at 4 hr but this increase was highly variable when expressed relative to liver protein content.
This allowed potentially toxic elevations in calcium concentration to be detected as early as 2 hr after acetaminophen overdose.
Research communications in chemical pathology and pharmacology  •  1987  |  View Paper