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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Caffeic Acid
Research Papers that Mention the Interaction
“ CA reduced the increased expression of growth arrest and DNA-damage-inducible protein (Gadd45)α induced by APAP in hepatocytes.”
Caffeic acid attenuated acetaminophen-induced hepatotoxicity by inhibiting ERK1/2-mediated early growth response-1 transcriptional activation.“ CA also reduced the increased cellular ROS level induced by APAP in hepatocytes.”
“The results of luciferase assay and Western-blot analysis showed that CA increased the transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the presence of APAP.”
“ CA also reduced the increased cellular ROS level induced by APAP in hepatocytes.”
“The results of luciferase assay and Westernblot analysis showed that CA increased the transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the presence of APAP.”
Paper alert.“The addition of inorganic ions (Mn(2+), Ca(2+), and Fe(3+)) and substituted phenols (guaiacol, caffeic acid , and p-coumaric acid) as co-solutes remarkably decreased the transformation rate of APAP.”
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