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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Ascorbate
Research Papers that Mention the Interaction
“Co-administration of the ascorbate esters AP or AS with APAP prevented an increase in liver weight/body weight ratios and hepatic glutathione depletion.”
Influence of ascorbic acid esters on acetaminophen-induced hepatotoxicity in mice.“The known potent inhibition of microsomally catalyzed covalent binding of acetaminophen by ascorbate has led to the suggestion that ascorbate rapidly reduces the reactive metabolite of acetaminophen and hence should protect against acetaminophen hepatotoxicity.”
“Interference from ascorbate and 4-acetamidophenol at both physiological and pharmacological ranges was significantly lower at the modified-carbon base electrodes than that at the unmodified-carbon base electrodes.”
Novel hexacyanoferrate (III)-modified carbon electrodes: application in miniaturized biosensors with potential for in vivo glucose sensing.
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