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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetaminophen
supplement:
Alcohols
Research Papers that Mention the Interaction
“Except for methanol and ethanol, all Investigated alcohols inhibited glucuronidation of paracetamol.”
Glucuronidation of paracetamol by human liver microsomes in vitro / enzyme kinetic parameters and interactions with short-chain aliphatic alcohols and opiates.“In C3H/HeN mice pretreated with the alcohols , subsequent exposure to APAP caused a transient decrease in liver nitrotyrosine formation, possibly due to competitive interaction of peroxynitrite with APAP producing 3-nitroacetaminophen.”
Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity.
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