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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acarbose
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“Our results indicated that the interaction between green tea extracts (green tea polyphenols or EGCG ) and acarbose was complicated.”
“The combination of green tea extracts, green tea polyphenols or EGCG with acarbose had a synergistic effect on α-amylase and α-glucosidase at low concentrations and the combined effect turned out to be antagonistic at high concentrations according to the Combination Index (CI) values.”
Combined Effects of Green Tea Extracts, Green Tea Polyphenols or Epigallocatechin Gallate with Acarbose on Inhibition against α-Amylase and α-Glucosidase in Vitro“The results showed that the α-glucosidase inhibitory activity of EGCG (IC50 = 19.5 ± 0.3 μM) was higher than that acarbose (IC50 = 278.7 ± 1.1 μM).”
Inhibitory effect of epigallocatechin-3-O-gallate on α-glucosidase and its hypoglycemic effect via targeting PI3K/AKT signaling pathway in L6 skeletal muscle cells.
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