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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acamprosate
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“We conclude that calcium is the active moiety of acamprosate.”
Acamprosate Produces Its Anti-Relapse Effects Via Calcium“Expert opinion: The recent discovery that large doses of calcium largely duplicate the effects of acamprosate in animal models has introduced a serious challenge to the widely held functional association between this drug and the glutamate neurotransmission system.”
“ Acamprosate also significantly reduced calcium entry caused by 80 mM K+ in control and ethanol-exposed cultures.”
Acamprosate is neuroprotective against glutamate-induced excitotoxicity when enhanced by ethanol withdrawal in neocortical cultures of fetal rat brain.
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