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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: 8-Chloro-Cyclic Adenosine Monophosphate and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

It is widely believed that ACTH stimulates cortisol secretion through adenosine 3',5'-cyclic monophosphate (cAMP), which provides substrate cholesterol by activating cholesterol ester hydrolase and facilitating transport of cholesterol to the side-chain cleavage enzyme.
The American journal of physiology  •  1984  |  View Paper
Moreover, the ACTH-dependent generation of c-AMP was significantly reduced as a result of in vivo treatment with ACTH.
Journal of steroid biochemistry  •  1982  |  View Paper
ACTH at concentrations of 0.01 mug/ml or more increased lipolysis and cAMP levels in both tissues.
The Journal of pharmacology and experimental therapeutics  •  1975  |  View Paper