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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“It is widely believed that ACTH stimulates cortisol secretion through adenosine 3',5'-cyclic monophosphate (cAMP), which provides substrate cholesterol by activating cholesterol ester hydrolase and facilitating transport of cholesterol to the side-chain cleavage enzyme.”
A mechanistic model of ACTH-stimulated cortisol secretion.“Moreover, the ACTH-dependent generation of c-AMP was significantly reduced as a result of in vivo treatment with ACTH.”
“ ACTH at concentrations of 0.01 mug/ml or more increased lipolysis and cAMP levels in both tissues.”
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