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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: 5-Hydroxytryptophan and Zimeldine

Research Papers that Mention the Interaction

After administration of zimeldine in combination with 5-HTP there was an increase in synchronized waking (W-2), followed by an increase in slow wave sleep (SWS), at first SWS-1 with spindles and then highly synchronized SWS-2.
Behavioural Brain Research  •  1987  |  View Paper
Long-term zimelidine and desipramine treatment reduced head twitch behaviour in mice induced by 5-HTP and 5-MeODMT.
Advances in biochemical psychopharmacology  •  1982  |  View Paper
On the other hand, PCPA abolished the post-stimulatory depressor response whereas 5-HTP and zimelidine had additive effects on the sciatic stimulation-induced depressor response, suggesting the involvement of central serotonin systems in the mechanism of the response.
Brain Research  •  1982  |  View Paper
Chlorimipramine, citalopram, fluoxetine, imipramine and zimelidine potentiated the low dose 5-hydroxytryptophan (5-HTP)-induced increase in prolactin secretion, suggesting inhibition of serotonin (5-HT) uptake by these drugs.
Acta psychiatrica Scandinavica. Supplementum  •  1981  |  View Paper
The 5-… inhibitors zimelidine (10 mg/kg IP 1.5 h pretest) or alaproclate (20 mg/kg IP 1.5 h pretest) … the ejaculation latency and of the post-ejaculatory interval in male rats treated with a subthreshold dose of 5-hydroxytryptophan (5-HTP) (12.5 … 1 h pretest).
Psychopharmacology  •  1980  |  View Paper