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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
5-Hydroxytryptophan
drug:
Mianserin
Research Papers that Mention the Interaction
“However, combined treatment of mianserin or maprotiline with either fluoxetine or 5-hydroxytryptophan significantly decreased beta-receptors even 24h after the last dose.”
Involvement of protein kinase in the regulation of beta-adrenergic receptors by antidepressants.“After a single administration only mianserin inhibited the L-5 hydroxytryptophan effect.”
“The behavioural syndrome induced by 5-hydroxytryptophan and clorgyline was only antagonized on acute treatment by mianserin.”
“The putative 5-hydroxytryptamine (5-HT) antagonists 2-bromo-LSD, cinanserin, cyproheptadine, pizotifen, methysergide, metitepine, mianserin and metergoline were found to reduce the frequency of the head-twitch response induced by intraperitoneal injections of 320 mg/kg of 5-hydroxytryptophan (5-HTP) in the rat.”
“The potentiation of the extensor reflex of hind limbs of the spinal …, induced 20 hours after the reserpinization by pretreatment with isocarboxazid and 5-HTP was suppressed by Mianserin , even in a low dose of 0.5 mg/kg, and by amitriptyline in a dose of 10 mg/kg.”
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