Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 months ago

Possible Interaction: 5-Hydroxytryptophan and Ketanserin

Research Papers that Mention the Interaction

Intraperitoneal (i.p.) injection of nantenine (13.3, 20 …) as well as the 5-HT2A receptor antagonist ketanserin (0.0625, 0.…/kg) inhibited the 5-hydroxy-L-tryptophan (l-5-HTP; 75 mg/kg, i.p.) plus monoamine oxidase …/kg, i.p.)-induced HTR in a dose-dependent manner.
injection of nantenine (13.3, 20 and 30 mg/kg) as well as the 5-HT2A receptor antagonist ketanserin (0.0625, 0.25 and 1 mg/kg) inhibited the 5-hydroxy-L-tryptophan (l-5-HTP; 75 mg/kg, i.p.)
Life sciences  •  2002  |  View Paper
Methysergide, RP62203, ketanserin , ritanserin and MDL11939 antagonized the inhibitory effects of 5-hydroxytryptophan or reversed the inhibitory effects to one of disinhibition.
British journal of pharmacology  •  1995  |  View Paper
ICV ketanserin (7.5 micrograms/5 microliters/5 min) also blocked response suppression induced with systemically administered 5-HTP.
Pharmacology Biochemistry and Behavior  •  1995  |  View Paper
Ketanserine injection clearly prevented the anti-aggressive effects of 5-HTP but caused a decrease of feeding.
Behavioural Brain Research  •  1989  |  View Paper
The anticonvulsant effect of 5-HTP against electroconvulsions in rats could be attenuated by the S2 receptor antagonist, ketanserin.
Neuroscience Letters  •  1985  |  View Paper