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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: 5-Hydroxytryptophan and Folic Acid Antagonists

Research Papers that Mention the Interaction

5HT-2-binding sites fulfil the criteria for receptors: binding affinity of antagonists to these sites correlates significantly with their potency to inhibit behavioral excitation in rats elicited by 5-hydroxytryptophan or 5HT agonists.(ABSTRACT TRUNCATED AT 250 WORDS)
Pharmacopsychiatry  •  1985  |  View Paper
These data demonstrate that central administration of 5-HT2A/2C antagonists potently attenuate operant response suppression induced with systemically administered 5-HTP or DOI and are in agreement with previous findings suggesting central mediation of 5-HTP-induced operant response suppression.
Pharmacology Biochemistry and Behavior  •  1995  |  View Paper
Both antagonists effectively prevented, at least partially, the inhibitory actions of 5-HTP.
Pharmacology Biochemistry and Behavior  •  1992  |  View Paper
In the present study, the thermogenic actions of 5-HTP , like those of 5-HT, were significantly reduced by pretreatment (5 min before) with the CRF antagonist alpha-helical CRF9-41 (25 micrograms, i.c.v.) or a polyclonal antibody to CRF.
Brain Research  •  1992  |  View Paper
Both antagonists cause a significant delay of the cell division which, however, can be prevented by the addition of either 5-hydroxytryptophane , serotonin, or 5-methoxytryptamine.
Developmental biology  •  1983  |  View Paper
These effects of 5-HTP were reversed by the 5-HT antagonists , cinanserin (4 mg/kg) and methysergide (2 mg/kg).
The Journal of pharmacology and experimental therapeutics  •  1978  |  View Paper
The results of this study indicate that Phe and 5-HTP are mutually antagonistic in modulating audiogenic seizure suceptibility.
Pharmacology Biochemistry and Behavior  •  1975  |  View Paper
It is concluded that the 5-HT antagonists will effectively antagonize the excitatory, but not the depressant, effects of 5-HTP on evoked potentials in the spinal cord.
Pretreatment with a 5-HT antagonist also prevented the excitatory effects of 5-HTP.
The amount of antagonist necessary for complete reversal was directly proportional to the dose of 5-HTP.
The Journal of pharmacology and experimental therapeutics  •  1968  |  View Paper