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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
5-Hydroxytryptophan
drug:
Diazepam
Research Papers that Mention the Interaction
“HGH release by L-5-HTP was not observed in these treatments of glucose or diazepam, therefore it might suggest that HGH release by L-5-HTP was inhibited by hyperglycemia or diazepam administration.”
Effect of L-5-HTP on the release of growth hormone, TSH and insulin.“The accumulation of 5-hydroxytryptophan (5-HTP) was also unaffected by stress but, like DOPA accumulation, was reduced to a small degree by diazepam.”
Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: Antagonism by diazepam“… diazepam in moderate dosage (1–10 mg/… caused a decrease in dopa and 5-hydroxytryptophan (5-HTP) formation, measured as the accumulation of these intermediates induced by inhibition of the aromatic L-… by means of NSD 1015 (3-hydroxybenzylhydrazine (HCl), in limbic forebrain, striatum and the remaining hemisphere portion.”
“The harmaline+5-hydroxytryptophan syndrome was blocked by drugs acting at benzodiazepine receptors (CL 218,872 greater than ethyl-beta-carboline-3-carboxylate, clonazepam, diazepam , Ro 15-1788, pentobarbital), and baclofen.”
“ Diazepam reduced the rise in secretion of prolactin during proestrus and the increase in release induced by stress, administration of fluoxetine plus 5-hydroxytryptophan and haloperidol.”
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