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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
5-Hydroxytryptophan
drug:
Dexamethasone
Research Papers that Mention the Interaction
“It is concluded that L-5-HTP loading may augment ACTH and, consequently, cortisol escape from suppression by dexamethasone in major but not in minor depressed subjects.”
Effects of serotonin precursors on the negative feedback effects of glucocorticoids on hypothalamic-pituitary-adrenal axis function in depression“The results show that the acute administration of L-5-HTP may increase the escape of β-endorphin secretion from suppression by dexamethasone in major, but not minor, depression.”
“Basal serum concentrations of prolactin (PRL) and the elevation of serum PRL concentrations induced by the serotonergic agents, quipazine and 5-hydroxytryptophan (5-HTP) were suppressed in rats treated acutely with dexamethasone.”
Effects of acute and chronic dexamethasone treatment on stimulated prolactin secretion in the rat.
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