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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: 5-Hydroxytryptophan and Desipramine

Research Papers that Mention the Interaction

Resupplying 5HT by by-passing trptophan hydroxylase inhibition, by administering 5-hydroxytryptophan , converts a DMI non-responsive to a DMI responsive beta adrenoceptor population and shifts the markedly decreased agonist affinity towards the affinity values found in control preparations.
Experientia  •  2005  |  View Paper
Pretreatment with a sub-effective dose of T3 (0.06 mg/kg) markedly enhanced the ability of drugs acting mainly on noradrenergic systems (clenbuterol, desipramine , maprotiline and nomifensine) to increase the response to L-5-HTP.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  1989  |  View Paper