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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
5-Hydroxytryptophan
drug:
Clonidine
Research Papers that Mention the Interaction
“ Clonidine also potently inhibited this response when produced by 5-hydroxytryptophan (5-HTP) and carbidopa.”
The influence of central noradrenergic function on 5-HT2-mediated head-twitch responses in mice: Possible implications for the actions of antidepressant drugs“ Clonidine by itself decreased the excitability of MNS and antagonized the excitatory effects of 5-HTP and TRH.”
“This locomotion-triggering effect of L-DOPA or clonidine was also observed when given after DL-5-HTP or apomorphine.”
“ Clonidine by itself decreased the excitability of motoneurons and antagonized the excitatory effect of 5-HTP and TRH.”
“In addition, clonidine (12.5 and 25 microgram/kg body weight, IP), a central alpha-adrenergic agonist known to inhibit renin release, attenuated drinking during 1, 2 and 3 hours after 5-HTP was administered.”
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