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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: 5-Hydroxytryptophan and Clomipramine

Research Papers that Mention the Interaction

The 5-HTP syndrome was potentiated in order of potency by MA = 4-CA greater than CI greater than CP greater than 3-CA whereas A, 2-CA and DMI had no effect.
Acta pharmacologica et toxicologica  •  1977  |  View Paper
If the animals had been pretreated with reserpine and nialamide, chlorimipramine caused potentiation of the effects of 5-hydroxytryptophan in doses as low as 1 mg/kg.
It was found that imipramine and particularly chlorimipramine potentiated the effects of 5-hydroxytryptophan , tryptophan and nialamide on the extensor hindlimb reflex.
European journal of pharmacology  •  1970  |  View Paper