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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: 5-Hydroxytryptophan and Buspirone

Research Papers that Mention the Interaction

This effect of buspirone was enhanced by fluoxetine, 5-HTP , nimodipine, and nifedipine.
Psychopharmacology  •  2003  |  View Paper
The suppressant effect of 5-hydroxytryptophan was antagonized or reversed by buspirone , a partial agonist at postsynaptic 5-HT1A receptors, and also by the "silent" 5-HT1A receptor antagonist WAY 100635, but not by the full agonist 8-OH-DPAT.
Behavioural pharmacology  •  1998  |  View Paper
The decrease was due apparently to a reduced turnover of serotonin; the accumulation of 5-hydroxytryptophan after decarboxylase inhibition was also suppressed by buspirone , not only in hypothalamus but also in brain stem, hippocampus and striatum.
The Journal of pharmacology and experimental therapeutics  •  1989  |  View Paper