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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
5-Hydroxytryptophan
drug:
Antipsychotic Agents
Research Papers that Mention the Interaction
“Hyperactivity in raphe lesioned rats (raphe rats) was significantly suppressed by α-methyl-p-tyrosine (α-MT), tetrabenazine and neuroleptics such as chlorpromazine and haloperidol, but was reduced only with large doses of L-5-hydroxytryptophan (L-5-HTP).”
Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats“The antagonism of neuroleptics of various groups (chlorpromazine, chlorprothixene, clopenthixol, clozapine, flupenthixol, fluphenazine, haloperidol, levomepromazine, mepazine, perazine, perphenazine, pimozide, prochlorperazine, promazine, spiperone, thiopromazine, thioridazine, trifluperazine, trifluperidol, triflupromazine) towards L-5-hydroxytryptophan (5-HTP ) was assessed on the basis of inhibition of characteristic head-twitches.”
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