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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: 5-Hydroxytryptophan and Antidepressive Agents

Research Papers that Mention the Interaction

Acute pretreatment with clinically equivalent doses of antidepressive drugs has been observed to block D, L-5-hydroxytryptophan (5-HTP) induced behavioral depression in rats working on a food-reinforced operant schedule.
Pharmacology Biochemistry and Behavior  •  1984  |  View Paper
In manic-depressive patients, the uptake of L-5-HTP is increased during the depressive phase , while the uptake of L-DOPA, is increased during the manic phase.
L'Encephale  •  1975  |  View Paper
CONCLUSION l- -HTP ha s definitely got ant idepressant effect in patients of depression.
Asian journal of psychiatry  •  2013  |  View Paper
Urinary excretion of serotonin in depressed individuals significantly increased after antidepressant treatment by 5-hydroxy-tryptophane and/or selective serotonin re-uptake inhibitor (p < 0.01).
Analytical and Bioanalytical Chemistry  •  2011  |  View Paper