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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
5-Hydroxytryptophan
drug:
Amitriptyline
Research Papers that Mention the Interaction
“The potentiation of the extensor reflex of hind limbs of the spinal …, induced 20 hours after the reserpinization by pretreatment with isocarboxazid and 5-HTP was suppressed by Mianserin, even in a low dose of 0.5 mg/kg, and by amitriptyline in a dose of 10 mg/kg.”
[Effects of mianserin on functions of ascending and descending monoaminergic systems, using experimental models (author's transl)].“It was observed that AMI at low doses antagonized the head twitch response to L-5-hydroxytryptophan or 5-methoxytryptamine, as well as tryptamine-induced convulsions.”
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