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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
4-Aminopyridine
supplement:
Silymarin
Research Papers that Mention the Interaction
“Immunoblotting assay results revealed that silymarin reduced 4-aminopyridine-induced phosphorylation of ERK1/2.”
“In rat cortical synaptosomes, silymarin reduced glutamate release and calcium elevation evoked by the K+ channel blocker 4-aminopyridine but did not affect glutamate release caused by the Na+ channel activator veratridine or the synaptosomal membrane potential.”
Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats
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