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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
4-Aminopyridine
supplement:
Oxytocin
Research Papers that Mention the Interaction
“4-AP or 3,4-DAP … 900 μU. In the presence of 4-AP … oxytocin evoked by stimulation at 15 Hz increased maximally to about 8,000 μU and that evoked by … at 15 Hz induced a significantly higher release of vasopressin and oxytocin than stimulation at 3 Hz.”
Differential effects of potassium channel blockers on neurohypophysial release of oxytocin and vasopressin. Evidence for frequency-dependent interaction with the endogenous opioid inhibition of oxytocin release“In the presence of 4-aminopyridine or tetraethylammonium ions the evoked release of oxytocin was increased 8-9-fold and remained unaffected by naloxone.”
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