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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
4-Aminopyridine
supplement:
Methionine
Research Papers that Mention the Interaction
“The administration of 4-AP before M appeared to intensify the development of dependence, and was most probably due to the Ca2+-induced inactivation of NMDA receptors as a result of excess release of GLU when the 4-AP took effect.”
The effects of different 4-aminopyridine and morphine combinations on the intensity of morphine abstinence.“It was found that the pre-incubation of neurons in the 4-AP system with a concentration of 1·10−12 M led to a 17.0% synergistic decrease in the membrane potential after a subsequent treatment with 1·10−2 M 4-AP solution.”
Diluted Aqueous Dispersed Systems of 4-Aminopyridine: The Relationship of Self-Organization, Physicochemical Properties, and Influence on the Electrical Characteristics of Neurons“In the case of K+ … used in animal research, 4-aminopyridine blocked E. … chemotaxis between 10−3 M and, totally, 10−2 M, while motility was not affected at 10−2 M; on the other hand, tetraethylammonium chloride failed to inhibit either chemotaxis or motility at 10−2 M.”
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