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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
4-Aminopyridine
supplement:
Dietary Fiber
Research Papers that Mention the Interaction
“In addition, injection experiments provide evidence that TEA+ and 4-AP applied internally to normal fibres effectively block potassium outward current, whereas in exhausted fibres the block seems to be smaller.”
Modified K-channel gating by exhaustion and the block by internally applied TEA+ and 4-aminopyridine in muscle“Exposure of the mechanically sensitive receptive fields to 4-aminopyridine (100 microM-1 mM) caused pronounced action potential discharge in all fibres studied.”
“Conversely, a reduced evoked response was invariably observed in all the fibres tested in the presence of 4-AP.”
“Application of 4-AP to immature myelinated fibres leads to a delayed membrane depolarization with action potential burst activity in response to a single stimulus5.”
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