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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: 4-Aminopyridine and Cd2+

supplement:

Cd2+

Research Papers that Mention the Interaction

Depolarizing voltage commands from prepulse potential of -90 … the presence of tetrodotoxin (0.5 microM) and Cd2+ (100 microM) to potentials between -40 and +40 mV cause voltage activation of … sustained delayed rectifier-type outward currents, which could be selectively inhibited by 4-AP (0.3-3 … mM), respectively.
Journal of neurophysiology  •  1998  |  View Paper
The inhibitory actions of the Ca2+ antagonist Cd2+ , morphine and noradrenaline (exogenously added + endogenously released) on electrically evoked release of [3H]noradrenaline from superfused rat neocortical slices were strongly reduced when release was enhanced by 4-aminopyridine.
European journal of pharmacology  •  1983  |  View Paper