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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: 4-Aminopyridine and Capsaicin

supplement:

Capsaicin

Research Papers that Mention the Interaction

In contrast, capsaicin enhanced 4-AP induced epileptiform activity in vitro (1-100μM) and triggered bursting activity in vivo (100μM dialysis perfusion), which was abolished by the TRPV1 antagonist CZP.
Experimental Neurology  •  2013  |  View Paper
Capsaicin (200 microM) reversibly blocked both components of the transmitter-activated potassium conductance similarly to other potassium channel blockers such as Ba2+, quinine or 4-aminopyridine.
Neuroscience Letters  •  1984  |  View Paper