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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
4-Aminopyridine
supplement:
Caffeic Acid
Research Papers that Mention the Interaction
“Inhibition of AA metabolites of the lipoxygenase pathway by nordihydroguaiaretic acid, 5,8,11,14-eicosatetranoic acid, and caffeic acid results in a concentration-dependent inhibition of VIP release evoked by 4-AP.”
Release of vasoactive intestinal peptide in mouse cerebral cortex: evidence for a role of arachidonic acid metabolites“In the electrophysiological assay, although epileptiform … were increased at 10 µM CA … 4-aminopyridine , and area under the curve (AUC) and number of population spike were increased at 10 µM FA with … dependency was not confirmed, and no significant changes were observed at 1 µM and by CGAs alone.”
Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays
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