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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
3-Nitrotyrosine
supplement:
Sulforaphane
Research Papers that Mention the Interaction
“Further, treatment with SFN also reverses LPS-induced effects on nitrative stress (iNOS, nitrotyrosine ) in monocytes of ASD subjects.”
Differential regulation of Nrf2 is linked to elevated inflammation and nitrative stress in monocytes of children with autism“ SFN treatment also significantly inhibited cardiac lipid accumulation, measured by Oil Red O staining, and improved cardiac inflammation oxidative stress and fibrosis, shown by down-regulating diabetes-induced PAI-1, TNF-α, CTGF, TGF-β, 3-NT , and 4-HNE expression.”
Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway.“ SFN also almost completely prevented diabetes-induced cardiac oxidative damage (increased accumulation of 3-nitrotyrosine and 4-hydroxynonenal) and inflammation (increased tumor necrotic factor-α and plasminogen activator inhibitor 1 expression).”
“ Sulforaphane also prevented the increase in NADPH oxidase activity and the elevations of superoxide and 3-nitrotyrosine that were stimulated by LPS.”
Sulforaphane Induces Glioprotection After LPS Challenge.
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