“The infarct limiting ability of remifentanil was compromised when the dihydroethidium fluorescence positive cell percentage exceeded 50%, MDA concentration greater than 2 nmol/mg of protein and nitrotyrosine content exceeding 1.5 μg/mg of protein.”
“There was a trend towards an increased nitrotyrosine concentration with increasing dose of remifentanil , becoming significant when the dose was 20 μg/kg/min.”