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Last Updated: 3 years ago
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“In penes 3-nitrotyrosine was significantly decreased in L-NAME treated wild-type and vehicle treated knockout mice (p <0.05).”
Neuronal nitric oxide signaling regulates erection recovery after cavernous nerve injury.“The NOS inhibitor, L-NAME , inhibited the increase in the generation of superoxide, NT and NOx, but aggravated LV function and increased infarct size in the diabetic heart.”
“Conversely, coadministration of L-NAME resulted in marked reduction of injury, NT , and SN when compared with CI-1044 alone.”
“Inhalation of L-NAME markedly suppressed iNOS protein expression and nitrotyrosine production.”
“Tissues from pregnant rats treated with l-NAME , endotoxin at 10 &mgr;g/kg, and a combination of l-NAME and endotoxin had increased 3-nitrotyrosine immunoreactivity.”
“Both nitrotyrosine accumulation and radical formation were reduced by inhibition of nitric oxide synthase with N-nitro-L-arginine methyl ester , but not with the inactive D-isomer.”
“Most importantly, N(ω)-nitro-L-arginine methyl ester (L-NAME, a nitric oxide synthase inhibitor) decreased protein levels of nitrotyrosine and concomitantly increased expression of membrane-bound fractalkine after exposure to SP.”
TRIM28/TIF1β and Fli-1 negatively regulate peroxynitrite generation via DUOX2 to decrease the shedding of membrane-bound fractalkine in human macrophages after exposure to substance P.
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