“ Irbesartan also significantly reduced nitrotyrosine formation during the OGTT.Conclusions/interpretationThis study demonstrates that irbesartan reduces plasma levels of nitrotyrosine in diabetic patients and is effective in counterbalancing nitrotyrosine formation during acute hyperglycaemia.”
“ResultsCompared with baseline measurements, treatment with irbesartan (0.57±0.4 vs 0.35±0.3 µmol/l, p<0.01) but not placebo (0.58±0.3 vs 0.59±0.2 µmol/l) significantly reduced fasting nitrotyrosine levels.”