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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
3-Nitrotyrosine
drug:
Azelnidipine
Research Papers that Mention the Interaction
“ Azelnidipine inhibited it most potently among the Ca2+-channel blockers tested (azelnidipine, amlodipine, nifedipine, diltiazem, verapamil, and nicardipine) at … concentration of 10 μM. Longer stimulation with these agents induced the expression of inducible nitric oxide synthase and nitrotyrosine , with an increase of lactic dehydrogenase …, whereas azelnidipine suppressed these changes.”
“ Azelnidipine may inhibit nitrotyrosine expression and cell damage caused by overproduction of nitric oxide, suggesting a mechanism for its cardiovascular protective effect.”
Comparative Effects of Azelnidipine and Other Ca2+-Channel Blockers on the Induction of Inducible Nitric Oxide Synthase in Vascular Smooth Muscle Cells
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