“Using gas chromatography-mass spectrometry … 10-fold increase in 3-nitrotyrosine (NO2Y) content, a global marker of protein modification by … species, in proteins recovered from bronchoalveolar lavage of severe asthmatic patients (480 ± 198 μmol/mol tyrosine; n = 11) compared with … (52.5 ± 40.7 μmol/mol tyrosine; n = 12).”