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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: 3-Hydroxypropylmercapturic Acid and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

It was concluded that HPMA copolymer-bound DOX induced additional caspase-dependent apoptosis signaling pathways and the degree of the induction was higher, which led to more pronounced apoptosis when compared to free DOX.
Journal of controlled release : official journal of the Controlled Release Society  •  2001  |  View Paper
P1 conjugate, i.e. non-targeted HPMA copolymer bearing doxorubicin … via a biodegradable GlyPheLeuGly sequence, synthesized by direct copolymerization of HPMA … monomeric doxorubicin and thus without additional drug-free GlyPheLeuGly sequences is less effective compared to … synthesized by polymer analogous reaction and thus containing extra drug-free GlyPheLeuGly sequences.
Journal of controlled release : official journal of the Controlled Release Society  •  2008  |  View Paper