Possible Interaction: 3,4-Methylenedioxyamphetamine and Ubiquinone

“… CoQ10 … ( MDA , p<0.001 and p<0.01, respectively), elevated the activities of antioxidant enzymes superoxide dismutase (SOD, p<0.01) and catalase (CAT, p<… (p<0.05), and down-regulated the release of cytochrome c (cyto-c) into the cytosol (p<0.01) in cisplatin-treated cells.”

“In a dose-dependent manner, CoQ10 significantly decreased colon/body weight index, colon weight/colon length ratio, clinical evaluation and macroscopic scoring of UC, serum LDH, C-reactive protein, colon MDA , TNF-α, caspase-3 expression and increased the serum total antioxidant capacity.”

“Malonaldehyde MDA ) content was significantly decreased by CoQ10 and L-carnitine + CoQ10 supplementation.”

“ CoQ10 administered at a dose of 200 mg x kg(-1)per os for 7 days prior to shock induction, reduced the elevated levels of brain MDA , NO(x), and GSHPx level/activity due to redundancy.”

“Meanwhile, CoQ10 decreased the levels of LDH and MDA and increased the levels of SOD and GSH, thus playing a role in regulating oxidation level.”

“Our … CoQ10 treatment could significantly decrease … of oxidative products ( MDA ) and increase the activities of antioxidant enzymes (SOD and GSH) against oxidative stress, as well as decrease the levels of … proteins (Bax and Caspase-3) and increase the levels of anti-apoptotic proteins (Bcl-2) against apoptosis after SCI.”